Molecular evolution of cyclin proteins in animals and fungi

Abstract Background The passage through the cell cycle is controlled by complexes of cyclins, the regulatory units, with cyclin-dependent kinases, the catalytic units.It is also known that cyclins form several families, which differ considerably in primary ANTIFRIZZ MASK structure from one eukaryotic organism to another.Despite these lines of evide

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Exploring high-performance viscosity index improver polymers via high-throughput molecular dynamics and explainable AI

Abstract Data-driven material innovation has the potential to revolutionize the traditional Edisonian process and significantly shorten development cycles.However, the scarcity of data in materials science and the poor interpretability of machine learning pose serious obstacles to the adoption of this new paradigm.Here, we propose a pipeline that i

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Budget impact analysis of routinely using whole-genomic sequencing of six multidrug-resistant bacterial pathogens in Queensland, Australia

Objective To predict the cost and health effects of routine use of whole-genome sequencing (WGS) of bacterial pathogens Personal Lubricants compared with those of standard of care.Design Budget impact analysis was performed over the following 5 years.Data were primarily from sequencing results on clusters of multidrug-resistant organisms across 27

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